JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 63 No 3 (2018): Journal of the Chilean Chemical Society
Original Research Papers

REVIEW RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW

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  • Noor Ul Amin Mohsin,
  • Muhammad Irfan
Noor Ul Amin Mohsin
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Government College University Faisalabad
Muhammad Irfan
Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Government College University Faisalabad
Published September 12, 2018
Keywords
  • Resveratrol (RSV),
  • Wittig reaction,
  • aldol condensation,
  • natural molecules,
  • antitumor activity,
  • anti-Alzheimer activity
    • ...More
    Less
How to Cite
Amin Mohsin, N. U., & Irfan, M. (2018). REVIEW RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW. Journal of the Chilean Chemical Society, 63(3). Retrieved from https://www.jcchems.com/index.php/JCCHEMS/article/view/775

Copyright (c) 2018 Journal of the Chilean Chemical Society

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Abstract

 Resveratrol (RSV) is a polyphenol produced by different plant species having a variety of biological activities. Synthesis of hybrid molecules of RSV with different natural and synthetic compounds has been studied. These hybrid molecules have been prepared by using fused or merged techniques or by using some linker groups. Wittig method was mostly applied by using the appropriate ylides to prepare the RSV core. The hybrid molecules prepared by these techniques exhibited anticancer, anti-inflammatory, antioxidant, anti-alzheimer, metal chelating and enzyme inhibitory activities. These hybrid RSV molecules can serve as a lead compounds for the future design of new drug molecules.

 

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