JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 61 No 2 (2016): Journal of the Chilean Chemical Society
Original Research Papers

ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND

Yamin Bibi
Department of Botany, PMAS Arid Agriculture University Rawalpindi
Abdul Qayyum
Department of Agricultural Sciences, University of Haripur
Sobia Nisa
Department of Microbiology, University of Haripur
Abdul Waheed
William Harvey Research Institute, Centre for Experimental Medicine & Rheumatology, Queen Mary University of London
Muhammad Fayyaz Chaudhary
Preston Institute of Nano Science and Technology, Preston University, Islamabad
Vol 61, No 2 (2016): Journal of the Chilean Chemical Society
Published June 10, 2016
Keywords
  • Pistacia integerrima,
  • Analgesic,
  • Extract,
  • Ethyl acetate fraction,
  • Column chromatography,
  • Nucleic magnetic resonance
  • ...More
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How to Cite
Bibi, Y., Qayyum, A., Nisa, S., Waheed, A., & Fayyaz Chaudhary, M. (2016). ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND. Journal of the Chilean Chemical Society, 61(2). Retrieved from https://www.jcchems.com/index.php/JCCHEMS/article/view/15

Abstract

Plants have been source of fantastic natural compounds that range in complexity. Chemical studies on traditional medicinal plants have led to discovery of potent bioactive components. Pistacia integerrima belonging to family Anacardiaceae has been traditionally effective for rheumatic pain, analgesic and antipyretic effects and used in treatment of coughs, phthisis, asthma and dysentery. Natural products have served as basis for compounds to be utilized in drug discovery. Stem extract of Pistacia integerrima was investigated with the aim to find some novel components that can later be used as drugs or active pharmaceutical intermediates. Plant material was collected from Margalla Hills Islamabad, shade dried and subjected to cold maceration technique for extraction. Crude extract was partitioned into different fractions on polarity basis. Repeated normal and reverse phase column chromatography of ethyl acetate fraction supported by Thin Layer Chromatography have led to the isolation of pure single compound. Isolated compound was further analyzed towards structural elucidation using LC-MS, IR and NMR spectroscopy. Present finding will be a useful and novel addition in already known chemical components from Pistacia integerrima.

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