JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 62 No 1 (2017): Journal of the Chilean Chemical Society
Original Research Papers

GRINDING SYNTHESIS OF 2-AMINO-4H-CHROMENES USING 3,3-(BUTANE-1,4-DIYL) BIS (1,2-DIMETHYL- 1H-IMIDAZOLE-3-IUM)Br-CAN AS A NOVEL REAGENT

Mohammad Nikpassand
Department of Chemistry, Rasht Branch, Islamic Azad University
Leila Zare Fekri
Department of Chemistry, Payame Noor University
Parvin Ahmadi
Department of Chemistry, Payame Noor University
Published June 5, 2017
Keywords
  • Chromenes,
  • Benzyl alcohols,
  • Ionic Liquid,
  • Multicomponent reaction,
  • 1-Naphthol,
  • Malononitrile
  • ...More
    Less

Abstract

A clean and environmentally benign route to 2-amino-4H-chromenes has been developed via three-component condensation reaction of various benzyl alcohols, malononitrile and 1-naphthol, using a catalytical amount of CAN and a reusable ionic liquid 3,3-(Butane-1,4-diyl)bis(1,2-dimethyl-1H-imidazole-3-ium) bromide ([BDBDMIm]Br) as a catalyst at room temperature. The present methodology offers several advantages such as solvent-free conditions, excellent yields, simple procedure, mild conditions and reduced environmental consequences. The ionic liquid was recovered and reused. All of synthesized compounds were characterized by IR, NMR and elemental analyses. 

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