JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 69 No 1 (2024): JCChemS
Original Research Papers

Synthesis of novel lipoic acid derivatives

Juan Pablo Gonzalez-Gutierrez
Instituto de Ciencias Aplicadas, Facultad de Ingeniería, Universidad Autónoma de Chile, Chile
S. Moris
Centro de Investigación de Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Talca, Chile.
Claudio Barrientos
Centro de Investigación de Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Talca, Chile
Published October 6, 2024
Keywords
  • Lipoic acid,
  • Steglich esterification,
  • Lipoic derivatives
How to Cite
González-Gutiérrez, J. P., Moris, S., & Barrientos, C. (2024). Synthesis of novel lipoic acid derivatives. Journal of the Chilean Chemical Society, 69(1), 6054-6055. Retrieved from https://www.jcchems.com/index.php/JCCHEMS/article/view/2694

Abstract

Lipoic acid is a naturally occurring compound involved in biological processes with special reactivity due to its 1,2-dithiolane ring. The novel ALA derivatives were synthesized using the Steglich esterification in mild conditions and then concentrated and neutralized with yields of 45.1 to 81.2%.

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