JOURNAL OF CHILEAN CHEMICAL SOCIETY

Vol 62 No 3 (2017): Journal of the Chilean Chemical Society
Original Research Papers

MOBILITY OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS IN SOILS WITH AND WITHOUT AMENDMENT OF BIOSOLID

Loreto Ascar
Departamento de Química Inorgánica y Analítica, Facultad de Ciencias Químicas y Farmacéuticas. Universidad de Chile
Inés Ahumada
Departamento de Química Inorgánica y Analítica, Facultad de Ciencias Químicas y Farmacéuticas. Universidad de Chile
Natalia Morales
Departamento de Química Inorgánica y Analítica, Facultad de Ciencias Químicas y Farmacéuticas. Universidad de Chile
Tatiana Garrido
Departamento de Química Inorgánica y Analítica, Facultad de Ciencias Químicas y Farmacéuticas. Universidad de Chile
Ady Giordano
Departamento de Química Inorgánica, Facultad de Química, Pontificia Universidad Católica de Chile
Karla Leiva
Departamento de Química Inorgánica y Analítica, Facultad de Ciencias Químicas y Farmacéuticas. Universidad de Chile
Published September 2, 2017
Keywords
  • Anti-inflammatory drugs,
  • mobility,
  • solid-phase extraction,
  • HPLC-DAD

Abstract

Nonsteroidal anti-inflammatory drugs are widely used by humans as therapeutic agents to treat or prevent illnesses. Once ingested, part of them is excreted and enters the wastewater treatment plants generating biosolids that they may be used as fertilizing complements.

The purpose of this study was to investigate the mobility of nonsteroidal anti-inflammatory drugs (ketoprofen, naproxen, diclofenac and ibuprofen) in soils and soils amended with biosolid.

Studies of NSAIDs adsorption on two different soils were carried through batch equilibrium at room temperature. The mobility of NSAIDs in soils was studied through the use of leaching columns incorporating in the top section soil enriched with NSAIDs with and without biosolid.

Ketoprofen, naproxen and ibuprofen were determined in the leaching columns. Anti-inflammatory mobility in the soil profile depends on the specific characteristics of each system soil-biosolid. In both soils there was little mobility of anti-inflammatory in the soil profile. In Linderos soil were found in greater quantity of Ibuprofen, naproxen and diclofenac that in Lonquén soil.

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